The Next Generation of the Vaccine : NANO VACCINE



Vaccination has greatly improved human health. Despite of all improvements in this field, there is not an efficient vaccine for many diseases, and of the available ones, some could not produce a long-term immunity. The emergence of nanotechnology and its development has had a great influence on vaccine and its delivery systems. Recently, there have been many researches on the applicability of nano-structures as an efficient system for vaccine delivery, and the initial results have been promising. The main nano-particles used in vaccine delivery, including polymeric nano-particles, inorganic nano-particles, liposome, virus-like particles, and virosomes. Many polymeric nano-particles have been used for vaccine delivery, including gelatin, alginate hyaluronic acid and chitosan which the latter is the most used polymer in the field of vaccine formulations. Alginate-based nano-particles are another group of nano-particles that have attracted the attention of researchers for vaccine delivery.  Nano-structures play two main roles in vaccine formulations: firstly, they are used as a vehicle for the delivery of vaccines, and, second, due to their intrinsic adjuvanticity, they could improve the immune. Newer generations of vaccines are safer, but they are not able to produce long life immunity and there is a need for repeated administrations. Nano-particles have been used more than any other types of nano-materials in vaccine formulations.


Although new generations of the vaccines are safer than the old ones, they are not so efficient in provoking of immune responses. For overcoming this obstacle, there have been many researches on the capability of nano-particles as a carrier for vaccine delivery in recent years. The possibility of targeting is a great feature of the delivery of vaccines by Nano-particles especially. 

To Know more about visit Pediatric Vaccination and Child Immunization

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